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Product Description:
Ginseng, perennial herbaceous plants, like a cool, moist climate, more than in 500 ~ 1100 meters above sea level mountain of small temperature difference between day and night in gentle slope or the slope of mixed needle or miscellaneous wood in the forest.Because the root hypertrophy, shape if the spindle, often have split ends, all seemingly people head, hand, foot and limbs, so called ginseng.Ginseng growth in one thousand, is extremely rare, very high medicinal value.
Organic acids and esters are: Citric acid, Isocitric acid, Fumaric acid, Ketone glutaric acid, Oleic acid, Linoleic acid, maleic acid, malic acid, pyruvic acid, succinic acid, tartaric acid, ginseng acid, salicylic acid, vanillic acid, hydroxy cinnamic acid, triglyceride, palmitic acid, three hexadecanoic acid glyceride, α,γ-Two palmitic acid glyceride, trimethylene triolein, glycosyl diacylglycerol.
Aimed at the study's results, from the British Liverpool's university professor of clinical epidemiology, Simon Capewell thinks its not involved in the study, Dr Reduced the mortality, is to improve people's diet, smoke less, as well as the embodiment of the medical progress.But unfortunately, the number of deaths caused by these diseases, is still staggering.
Product name: GMP Top100%Natural Ginseng Chewable,Nourilieve fatigue,Resist radiation Anticance,Enhance Memory, Enhance Immunity Protection of heart head blood-vessel,Relieve fatigue, Health Food,Nourishing beauty,Anticance,Protect liver, Reinforce vital energy, Enhance Immunity, ,Resistance to disease, Anticancer, Antitumor,Antiaging, Pure natural health food, No pigment, No preservatives.Prolong life.
Specifications:
400Bottles/Box;500mg*100Tablets/Bottle
200Bottles/Box;500mg*200Tablets/Bottle
160Bottles/Box;500mg*300Tablets/Bottle
1 g *100Tablets/ bottle; 240bottles/box
1 g *200Tablets/ bottle;120bottles/box
1 g *300Tablets/ bottle;80bottles/box
MOQ: 100Boxes.
Shelf life :24 months
100% natural active ginseng Chewable, enhance immunity, antivirus, antitumor, resistance to radiation, anticancer,<< Botanical medicinal materials> >prolong life .
Source China the only suitable for ginseng growth of the original ecological planting base of high quality fresh ginseng as raw material, adopt low temperature vacuum freeze drying, micro powder" world advanced biological engineering technology such as refined processed.Products effectively keeps the ginseng saponins of fresh ginseng, ginseng polysaccharides such as all kinds of natural bioactive substances.This product use convenient, easy to absorb, not hot not dry, the four seasons all appropriate, does not contain any preservatives and additives.Is the preferred new green tonic.
Main ingredients: 100% active ginseng
Appropriate crowd: frail, sub-health population, etc.
Usage and dosage: Oral, 2 times a day, every time 1 Or 2 tablets.
Do not taken precautions: Turnip, strong tea, can't be Shared with hellebore
Shelf life: 2 years
China organic ginseng live advantageous geographical environment, the unique source of water, the unique climate, unique environment, the details are as follows:
1. Unique Source of water: One of the world s three big alkaline mineral water of production place , China's deepest lake, changbai mountain tianchi, located in southeast China, jilin province, is China and north Korea's tianchi lboundary lake, north of the lake in jilin province, is the source of the songhua river. Because it's position is high, the water surface elevation 2150 meters, so called Tianchi.
Along with the Alps in Europe, Russia Caucasus mountain enjoy equal popularity, spread all over the rich selenium mineral spring, for organic ginseng transport nutrients.
Pour down from tianchi changbai waterfall fly, the biggest fall of volcanic lake is one of the world, it rumble like thunder, The water splashed in all directions, fog is cover sky. jinjiang waterfalls is located in royal crown south, Two fall converge into a mighty torrent, droped trough, heartquake, with tianchi waterfall a north and a south , echo each other at a distance, the spectacular. Vividly the reappear suspected order Longchi of spray auspicious snow, it like the sky hang flight flow torrents "magical realm, swimmers be personally on the scene, can produce fine rain drift, The ease of ice-cold heart be pleased feeling.
2.Unique Of Climate: China's Changbai mountain known as: one thousand snow cover and selaginella tamariscina, straight up first on the highest peak reputation in the world.A year for 7 ~ 8 months is covered by snow, the minimum temperature of 40 degrees below zero, has produced more purity of the original ecological environment in low temperature.
Perennial original forest floor timeout and thick accumulation of leaves natural fertilizer, not only suitable for ginseng growth, also all kinds of rare wild edible fungus growth.
3.Unique Of Environment: One of three natural resources treasure in China, in 1980 to join the United Nations - man and biosphere, reserve network, to become the world's great natural original ecology environmental protection one of the best reservation, known as the natural museum.
Ginseng, perennial herbaceous plants, like a cool, moist climate, more than in 500 ~ 1100 meters above sea level mountain of small temperature difference between day and night in gentle slope or the slope of mixed needle or miscellaneous wood in the forest.Because the root hypertrophy, shape if the spindle, often have split ends, all seemingly people head, hand, foot and limbs, so called ginseng.Ginseng growth in one thousand, is extremely rare, very high medicinal value.
Top organic Ginseng nutrition value:
Red ginseng(Also called cooked gingeng), sun-dried ginseng or white ginseng of the a total extract more than 30 kinds of ginsenoside (can be divided into three groups, namely oleanolic acid group, the protopanoxadiol group and raw panaxatriol group), respectively called ginseng saponins (Ginsenoside) - RX (Note: X = 0, a1, a2, a3, b1, b2, b3, c, d, e, f, g1, g2 and g3, h1, h2, h3, s1, s2), there are fake ginseng saponins F11, etc. Ginsenoside for ginseng physiologically active material basis , When the separation aglucone ,due to the effect of dilute acid, molecular side chain of hydroxyl and olefinic bond cyclization and Ginseng two alcohol and ginseng three alcohol, Ginseng two alcohol and ginseng three alcohol all are triterpene compounds.
Among them especially antitumor effect of RH2 ginsenosides in which is the strongest, enhance immunity, relieve fatigue effect is best, in the medical journal has published its efficacy. But RH2 ginsenosides in ginseng content rarely, very expensive.
Organic acids and esters are: Citric acid, Isocitric acid, Fumaric acid, Ketone glutaric acid, Oleic acid, Linoleic acid, maleic acid, malic acid, pyruvic acid, succinic acid, tartaric acid, ginseng acid, salicylic acid, vanillic acid, hydroxy cinnamic acid, triglyceride, palmitic acid, three hexadecanoic acid glyceride, α,γ-Two palmitic acid glyceride, trimethylene triolein, glycosyl diacylglycerol.
Vitamins are vitamin B1, vitamin B2, vitamin B12, vitamin C, nicotinic acid, folic acid, pantothenic acid, biotin, nicotinamide.
Sterol and their glycosides are: beta sitosterol, stigmasterol, daucosterol, campesterol, ginseng saponins P and ester sterol.n addition, ginseng is still contains: adenosine invertase, L - aspartate enzyme, beta amylase, sucrose invertase;Maltol, including alkanes, kaempferia galanga phenol, ginseng flavone glycoside, and copper, zinc, iron, manganese and other 20 kinds of trace elements.
Saponins of ginseng stem leaf, and root are consistent basically.Ginseng, ginseng buds, and leaves, and flowers, and fruit, such as the content of total saponins, is higher than the root, is worth further use.
Modern research:
1. Chemical composition: this product contains a variety of ginseng saponins, volatile oil, amino acids, trace elements and organic acids, sugars, vitamins, etc.
2. The pharmacological effects: antibody g effects of ginseng, ginseng injection in patients with uncontrolled hemorrhagic shock and acute toxic shock than other causes of shock, is especially significant effect;Can make the heart beat vibration amplitude and heart rate increased significantly, in heart failure, cardiac function more significantly;Can exciting pituitary adrenocortical system, improve the ability of stress reaction;The excitement and inhibition process of higher nervous activity has enhanced role;Can enhance the flexibility of neural activity process, improve the mental work function;Fatigue, promote the synthesis of proteins, RNA, DNA, promote the function of hematopoietic system, regulating cholesterol metabolism, and so on;Can enhance the body's immune function;Can enhance function of gonad, gonadotropin sample function;Can reduce blood sugar.In addition, there are anti-inflammatory, anti-allergic, antidiuretic and antitumor effect.Ginseng pharmacological activities often due to the body to form different a two-way role.
3. Clinical research: it is reported that the oral ginseng capsules crystal (Each containing ginsenoside 40 mg), 2 times /day, 1 time 1 grain, treatment of spleen and kidney deficiency syndrome type 2 diabetes mellitus patient 30 cases were obviously lower blood sugar function (New traditional Chinese medicine, 2000, 7:44).With ginseng injection used in 30 cases of leukemia patients undergoing chemotherapy, the digestive tract reaction caused by chemotherapy and the effect of myocardial enzyme changes significantly lower than the control group (new traditional Chinese medicine, 2000, 5:19).With ginseng in the treatment of 27 patients with impotence, 15 cases of sexual function recovery, 9 cases, 3 cases ineffective;Or take ginseng extract 500 mg per day, to treat senile secondary sexual dysfunction, have certain curative effect (jilin medicine, 1983, 5:54);Capsule oral ginseng total saponins, 2.4 ~ 3.0 g per day, has certain effect in treatment of renal anemia (comprehensive clinical medicine, 1993, 4:209).This product is commonly used to treat shock, cor pulmonale, leukopenia, chronic hepatitis, viral myocarditis, a variety of diseases such as cancer.
Ginseng suitable for the croud:
1. Suitable for weak people, less blood, shortness of breath, anemia, and postpartum women, such as convalescence patients with neurasthenia.
2. Solid heat syndromes, damp heat syndrome and the vital qi is not virtual clothing.
However, taking ginseng need according to the constitution.Afraid of the cold body must be on the red ginseng.
The body can't stand the heat of people must be on white ginseng.And, can't take more every day.
Health dose: 1 ~ 2 grams per day.Treatment need 3 ~ 4 grams per day.Remember that in large doses, may not lead to flow nosebleed, and other symptoms.
Ginseng rare homology of medicine and food - Health care treasures -
Chinese medicine known as ginseng is a tonic medicine, able to replenish the loss of nutrients, nourish five organs. Ginseng has driven the rightness of human life movement and WenZhao magical efficacy and role. Long-term edible can prolong life.
1. Organic ginseng can increase sexual desire and sperm vitality, husband and wife sex harmony:
Soure, ginseng is a tonic medicine, ginseng can increase the number of sperm production and improve sperm activity frequency, so men eat ginseng can enhance the vitality of the sperm, and nourishing WenJian with energetic in nature gas, longer than the sun be the spirit, is suitable for the emergency back to Yang.Ginseng can also increase the more vitality and promote blood circulation of pubic improve men's and women's sexual desire.Make couples sex life more harmonious, more happy happiness.
2. The role of organic ginseng to middle age, old age:
Organic ginseng contains rich ginseng saponin, amino acid, iron, calcium, ginseng enzymes, minerals and vitamins, naphtha, etc.Can nourish Yin raise colour, educational brain, enhance memory.Restores the physical strength, eliminate fatigue, can clear the production of body fluid, vigour and treatment of massive hemorrhage, throat dry, weak vexed, senior natural health care products is very suitable for old people to enjoy.
3.Organic ginseng is a natural beautician:
Organic ginseng is rich in ginseng saponins, ginseng triol, a variety of minerals and vitamins, has good cholesterol and promotes the leather shoes of capillary blood asked, increase the skin nutrition, prevent arteriosclerosis, and so on, so can retard skin aging effect;
Organic ginseng is rich in ginseng saponins, ginseng triol, a variety of minerals and vitamins, has good cholesterol and promotes the leather shoes of capillary blood asked, increase the skin nutrition, prevent arteriosclerosis, and so on, so can retard skin aging effect;
Organic ginseng is contained in minerals can adjust the balance of skin moisture, prevent the skin drying dehydration, enhance skin elasticity, has the wrinkle resistance, anti-aging, beauty of magical effect.
4. Organic ginseng Strengthens the bone marrow hematopoietic function:
Ginseng can promote ribonucleic acid (RNA), deoxyribonucleic acid (DNA), protein, cholesterol, fat and sugar metabolism, promote bone marrow cell mitosis, is blood red blood cells, white blood cells and bone marrow nucleated cell count increased, resulting in increased bone marrow hematopoietic function.Ginseng protect against low radiation loss of bone marrow.
Bone marrow description:
Hematopoietic tissue in the body, is located in the medullary cavity of long bone and within all cancellous bone.Adult bone marrow is divided into two kinds: red marrow and yellow marrow.Red marrow to produce red blood cells, platelets and various white blood cells.Platelets have hemostatic effect, white blood cells can kill and restrain all kinds of pathogens, including bacteria, viruses, etc.;Some lymphocytes to produce antibodies.As a result, the bone marrow but not hematopoietic organs, it is also important immune organs.Physiology term editor
Definition:
Bone marrow is found in long bone (For example, Humerus, Femur) in bone marrow cavity, flat bone (For example,ilium, ribs) and irregular bones (such as bone, vertebra) between the cancellous bone of mesh, a spongy tissue can produce slightly red blood cells of bone marrow, called red marrow.Some adult bone marrow contains a lot of fat cells in the marrow cavity, yellow, and does not produce blood cells, known as the yellow marrow.People were born, the whole body bone marrow cavity filled with red marrow, as we age, bone marrow fat cells increased, some red marrow was replaced by the yellow marrow, finally only almost flat red marrow in cancellous bone.Such changes may be due to the adult without all the medullary hematopoiesis, part of the medullary hematopoiesis has enough supply blood cells.When the body severe ischemia, part of the yellow marrow can be transformed into red marrow, restore hematopoietic capability.
Function:
Blood in the human body composition is in a constant metabolism, the old cells were removed, generate new cells, the important function is to produce a variety of bone marrow cells of stem cells, the stem cells regeneration through differentiation into various cells such as red blood cells, white blood cells, platelets, simply is the role of bone marrow hematopoietic function.Therefore, to maintain the body's bone marrow life and immunity is very important.
Bone marrow is the source of human body central nervous, hematopoietic, the source of hematopoietic stem cell incubator, immune.The elderly should keep kidney essence and blood know luo, prevention of bone degeneration.Joint degeneration is a common disease in the elderly, bone disease is not necessarily a calcium deficiency, there are many reasons.Is also a lot of people in the middle age it is important to note that a disease, therefore, should pay attention to the nutrition supplement and adjustment at ordinary times, especially after age 50, more need to complement and aftercare, don't wait for bone marrow emptiness to aftercare.
Skeleton in the human body effect:
Skeletal system generally people only know the skeleton is used to support the body, but forgot the bone marrow is the important place to produce white blood cells such as immune substances, the human body every second with eight million blood cell death, and bone marrow were able to generate the same number of new cells to supplement.For example, production of B lymphocytes in the bone marrow, can produce all kinds of antibodies to the invaders, main body is humoral immunity, when problems arise in the bone marrow, immune cell metabolism will be affected, serious still can cause leukemia.
Bone marrow is the source of human life, human life is like a candle, bone marrow, it is a candle, folk adage said: The Spring Silkworms go to die silk deplete, candles burn to ashes
tears dry,this is to describe things, or the end of life.When a candle wax oil runs out, the candle will be extinguished.A man's life, the bone marrow run out time, the person's life will end, a man's life will end.
The human body made sperm (Including a variety of endocrine and saliva), made sperm, immune cells, natural healing power, and every day in the human body to increase acid poison, etc., are relying on bone marrow released every bit of the completion of these tasks.So the height of the human body as the growth of the age and gradually atrophic, this is because of the loss of bone marrow, usually Some nutritional deficiencies of pregnant women, each postpartum loose teeth or even fall off one or more, hips are all largen, this is because a large number of intake by fetal bone marrow, and lead to loss of bone marrow and the cause of osteoporosis;Now medical thought marrow renewable 14 days or so.
The ancient saying goes: A drop of blood, ten drops of sperm , ten drop of sperm ,a drop of bone marrow. Ancient people also like to use the sperm and marrow two words to something or the essence or substance of things, so, the bone marrow to the importance of the human body.
Abstract: Died of a heart attack and apoplexy is still increasing significantly of the world's population.
Cardiovascular disease, cancer, diabetes, HIV/AIDS, known as the world's biggest health killer, the four major disease mortality is caused by other diseases cannot be compared
Aimed at the study's results, from the British Liverpool's university professor of clinical epidemiology, Simon Capewell thinks its not involved in the study, Dr Reduced the mortality, is to improve people's diet, smoke less, as well as the embodiment of the medical progress.But unfortunately, the number of deaths caused by these diseases, is still staggering.
Dr Capewell said: The death caused by the disease, and many belong to an early death, that is, the patient was died 75 years ago. But in fact, 90% of this kind of premature death, is can be avoided through healthy diet and not smoking and prevention."
In the new study, the university of Washington in the United States institute of health indicators and assessment, researchers led by Dr Gregory Roth from 188 countries for the 2013 global disease statistical analysis data were evaluated, and focus on the 1990 ~ 2013 death cases of heart disease and mortality.Here, researchers will heart disease is defined as a kind of disease, including heart attacks (heart attacks), stroke, rheumatic heart disease, aortic aneurysms, and other diseases, etc.
The research results show that in 1990, the world about 12.3 million people died of a heart attack;But by 2013, the number has increased to 17.3 million, its growth rate reached 40%.The researchers believe that the world's population aging is the main cause of this phenomenon.And the growth of the world's population, it is another important factor.
The results also show that only heart disease deaths in Western Europe and central Europe, fell over the same period.All this is obviously different, global mortality from heart disease, all fell over the same period, and the average of 39%.
According to these results, a university of California, San Francisco, stroke center, medical director of Anthony Dr Kim said: "things are getting better. Although heart disease is still the main cause of death of the American people and but in the cause of stroke in the top position, has been in previous years the third drop to fourth place, and was recently dropped to fifth place."At the same time, Dr Kim also said: "in order to make the absolute increase in the number of deaths caused by heart disease and stroke situation reversed, now is necessary in the treatment and prevention of aspects to make greater efforts.
The study is published in the April 2, 2015 in the New England journal of medicine
The study is published in the April 2, 2015 in the New England journal of medicine
The abstract (10:43 September 26, 2007; China news) : According to the world health organization, the world has 17 million people die each year from heart bo the world heart federation's latest statistics show that, the world has a population of 1 billion overweight or obese, making obesity might replace smoking become the main cause of heart disease and stroke.The expert points out, want to have a healthy weight, healthy body, can make a healthy heart.
Clinically most, is the most fatal myocardial infarction, especially in autumn and winter seasons and every major holiday, is the season of myocardial infarction. Abroad have data show that in the patients with myocardial infarction, a third patient never know his illness lose life. The famous Chinese crosstalk performer hou is killed by myocardial infarction.
In addition, Source and phoenix sports (Sep 19, 2015,20:33P.M) - news information
The world the most handsome - the united Arab emirates (UAE) prince rasheed died of a heart attack, only 34 years old, and he died young, had taken the Asian games equestrian gold medal, For dubai several main partner investment firms and Banks, Forbes has been rated as one of the world's most popular young members of the royal family, also has won many international endurance awards.
A lot of things can be start again, but, life is only once. Regardless of wealth, status, love, career all is zero, the only health is one. Health is most important. So Pay attention to health is to give yourself and your family joy and happiness.
At the beginning of the last century, many scholars began to study the effect of ginseng on animal blood pressure. Because agents and different doses, the experimental results that the ginseng on blood pressure rising and falling or bipolar regulation but is given priority to with step-down three adjustment. Its mechanism is: (1) direct effects on vascular smooth muscle;Alpha 2 (2) and excitement of the presynaptic membrane with decreased sympathetic neurotransmitter release. In recent years, some scholars studied the ginseng stem leaf diol (PDS) and three alcohol group (PTS) saponins effects on blood pressure. The experiment showed that PDS main cause blood pressure to drop, the sample function and its quasi choline role;PTS intravenous injection can lead to high blood pressure, the effect may be related to alpha, beta receptors has nothing to do, but affects the central. The experiment through the booster is contained in the ginseng stem leaf total glucoside (PTS) and step-down (PDS), confirmed the ginseng total glucoside can cause blood pressure change of bipolar [16].
Organic ginseng can protect and prevent cardiovascular disease:
ReferenceGinseng effect on cardiovascular system of pharmacology experiment research new progress:
key words The ginseng saponins class;The cardiovascular system; Pharmacology
In recent years, around the ginseng research mainly focused on the ginseng saponins cardiovascular pharmacological research and discussion. Now that ginseng to myocardial ischemia/reperfusion injury has a protective effect, can resist arrhythmia, myocardial anti-shock protection, can effectively improve hemodynamics with cardiac function, can improve the ability of the body hypoxia can regulate lipid metabolism in order to play a role of resistance to atherosclerosis, etc. In this paper, the cardiovascular pharmacological effects of ginseng and its related mechanism were summarized.
1. The ginseng has protection of myocardial ischemia-reperfusion injury:
Ginseng total saponins (GS) of myocardial cells in vitro and a variety of animal experimental myocardial ischemia, myocardial infarction and reperfusion plays a protective role. The rabbit myocardial ischemia-reperfusion injury of protection, to 20 ~ 80 mg/L concentration range, and the effects increase with concentration;But when the concentration of 160 mg/L, but there is a tendency of increase myocardial ischemia-reperfusion injury. [1] jie-min zhang [2], such as further confirmed the relationship between concentration and effect, and also found that the GS sample with calcium antagonist effect, can reduce the reperfusion period myocardial intracellular calcium accumulation, thus reduce reperfusion. Ginseng total saponins mechanism against myocardial ischemia/reperfusion injury in addition to providing energy matrix, increase the level of the substrate phosphorylation, promote the adenosine triphosphate (atp), creatine phosphate synthesis, mainly due to its protection of myocardial cell mitochondria calcium pump activity, reduce mitochondrial membrane phospholipids degradation, complete protection system, reduce the concentration of intracellular ca2, prevent myocardial intracellular calcium overload, avoids the myocardial reperfusion injury [3].
Yuan Maokun etc. [4] by abdominal heterotopic rat heart transplantation model found PDS also plays a protective role to ischemic myocardial reperfusion injury, and the appropriate concentration of 40 mg/l. then further found that some scholars as high potassium cardiac arrest additive, PDS in 40 ~ 160 mg/L concentration range, the heart ischemia-reperfusion injury has a direct protective effect, its mechanism is the PDS can relieve the damage of myocardial mitochondria after ischemia reperfusion. But when the PDS concentration increased to 320 mg/L, the protection disappeared, but have a tendency to increase myocardial ischemia-reperfusion injury. And presented a PDS at low concentration is given priority to with the role of Rb components;When higher levels, some have side effects on myocardial components [5]. The advantage of monomer saponins, Re Rg2 on myocardial ischemia reperfusion also has obvious protective effect, its mechanism of action is significantly against ischemia-reperfusion injury induced myocardial apoptosis [6].
2. The Organic ginseng has antiarrhythmic effect:
2.1 characteristics of structure-activity AD [8] in ginseng, such as chemical composition and its anti-arrhythmic structure-activity relationship studies pointed out that: (1) when the aglucone, connect the sugar phase at the same time, the number of the active intensity sequence is: the original ginseng three glycol type > oleanolic acid type > original ginseng glycol type;For three sugar glucoside Re > Ro > Rd, the disaccharide glycoside Rg2 > Rg3, for monosaccharide glucoside Rh1 > Rh2;(2) when the aglucone and same, the number of connection of sugar is not at the same time, the intensity of the active order: ginseng three glucoside > ginseng disaccharide glycoside > ginseng monosaccharide glucoside, for example: the original ginseng three glycol type Re > Re2 > Rh1, former ginseng glycol type Rd > Rg3 > Rh2. Ginseng saponins of Re anti-arrhythmic activity most, its strength and lidocaine.
2.2 mechanism Wang Zhongfeng [9], such as adsorption with cell patch clamp method proved ginseng saponins Rg1 glycol group for the first time on rat myocardial cell L, T calcium channel blocking effects, and puts forward the mechanism is to make the calcium channel average open time shortened, lengthen the average closing time, open probability decreasing. Xue-jun li etc. [10] and Gao Baoying [11] found PTS in vitro and in vivo rat cardiac arrhythmia caused by ischemia reperfusion injury has obvious inhibitory effect. And the effect on the cardiac electrophysiology and amiodarone is similar, can make the in vitro in guinea pig papillary muscle cell action potential calendar and effective refractory period are extended, thus suggesting the effect may be caused by block potassium channels. Experimental studies have confirmed that the PDS and PTS can improve the activity of superoxide dismutase (SOD), content of oxygen to reduce myocardial superoxide anion free radicals, which play the role of resistance to free radical damage. Gao Baoying etc. [11] also found that PTS can inhibit rat sympathetic efferent activity, slow heart rate, lower blood pressure, and point out the effect and prolong the action potential to process and effective refractory period, reduce myocardial self-discipline, and the function of calcium in combination may be PTS against ischemia reperfusion arrhythmia of the mechanism.
3. The Organic ginseng has effects on hemodynamics:
The main composition of ginseng saponins of ginseng. So far, has been isolated from ginseng and determines the structure of the saponins content meter more than 40 kinds. Experiments show that they can effectively improve hemodynamics. Use ginseng total saponins of 20, 10 mg/kg intravenous anesthesia animals all can increase the coronary flow, resistance to drop, increase myocardial oxygen, and can make the heart rate slowed significantly, thus reducing myocardial oxygen consumption. But there is the different doses, high-dose intravenous injection can obviously inhibit left ventricular pressure rise maximum rate (LVdp/dtmax) and peak (LVSP), left ventricular pressure blood pressure to drop, but the heart pump function index of cardiac output (CO) and cardiac index (CI) has no obvious influence. And small doses of LVdp/dtmax and LVSP has no obvious change, systolic blood pressure rose slightly, but not significant [12].
In 40 ~ 160 mg/L concentration range, PDS with stable heart rate (HR), speed up the myocardial contraction and expansion rate (+ dp/dtmax) and improve the arterial pressure (ASP) and lower left ventricular end-diastolic pressure (LVEDP), increase the effect of CO. When PDS concentration increased to 320 mg/L, the effect disappeared, instead of a tendency toward hemodynamic negative increase in [13]. As one of three alcoholic ginseng saponins of ginseng saponins Rg2 have strong heart such as strophanthin K. Experiments show that the preparation of coronary artery ligation of cardiac shock animal models, LVSP Rg2 through higher + dp/dtmax and increase myocardial contraction force improve cardiac systolic and diastolic function.In a rabbit model of pentobarbital sodium (hf, Rg2 can improve cardiac insufficiency rabbit hemodynamic status, has the strong heart function at the same time, would not significantly increase myocardial work, also can improve myocardial blood supply (14 to 15).
At the beginning of the last century, many scholars began to study the effect of ginseng on animal blood pressure. Because agents and different doses, the experimental results that the ginseng on blood pressure rising and falling or bipolar regulation but is given priority to with step-down three adjustment. Its mechanism is: (1) direct effects on vascular smooth muscle;Alpha 2 (2) and excitement of the presynaptic membrane with decreased sympathetic neurotransmitter release. In recent years, some scholars studied the ginseng stem leaf diol (PDS) and three alcohol group (PTS) saponins effects on blood pressure. The experiment showed that PDS main cause blood pressure to drop, the sample function and its quasi choline role;PTS intravenous injection can lead to high blood pressure, the effect may be related to alpha, beta receptors has nothing to do, but affects the central. The experiment through the booster is contained in the ginseng stem leaf total glucoside (PTS) and step-down (PDS), confirmed the ginseng total glucoside can cause blood pressure change of bipolar [16].
4. The Organic ginseng has resistance to shock, protect myocardial function:
Numerous studies show that ginseng has shock myocardial protection against a variety of type. Use total saponins of ginseng to heart failure caused by pentobarbital sodium and source sex shock dogs after intravenous administration of their blood pressure, LVSP, LVdp/dtmax and CO are increased, LVEDP decreased, the heart rate slows, can alleviate the symptoms of heart failure and heart source sex shock dogs, and thus play a role of its resisting myocardial infarction [17]. Li Yingdeng [18] using light microscope and X-ray energy spectrometer, the method of the combination of ginseng fruit saponins was studied on the influence of uncontrolled hemorrhagic shock canine myocardial, found the ginseng fruit saponins in treatment group significantly reduce canine myocardial ultrastructure pathological changes, at the same time can increase the sarcoplasmic reticulum Ca2 +, reduce the mitochondria in the Ca2 +. The experimental results from the ultrastructure level and the distribution of Ca2 + level confirmed that ginseng fruit saponins have resistance to shock, protect myocardial function. Liu Xianfen [19] in the experimental study of shock ginseng injection in mice found that don't straight and liquid in mice by intraperitoneal injection, burn shock occurred after 5, 7 h mortality is significantly lower than the control group, but the mortality rate in the two groups no significant difference after 12 h. That don't straight and injection scald shock in mice that delay the mortality, and only can prolong the survival time.
5. The Organic ginseng has effects on lipid metabolism:
Lipid metabolism closely relationship with cardiovascular disease has been recognized. High cholesterol is a major cause of atherosclerosis (AS). In particular, serum cholesterol (TC) and low density lipoprotein (LDCC) leels are dangerous to the AS indicators. And high density lipoprotein (in HDLC) and AS a negative correlation, in HDLC/TC ratio, the greater the LDCC/in HDLC ratio is smaller, the effect of resistance is AS the stronger. On the rats with high fat feed at the same time give ginseng extract (PssNe) water, observe its effect on building model of lipid metabolism in rats, the results show that PssNe group than the control group can significantly reduce the rat serum TG, TC and LDLC/in HDLC ratio, increase in HDLC levels and in HDLC/TC ratio, has the obvious function of reducing blood fat and for regulating lipid metabolism, preventing the AS positive [20].
And lipid peroxidation and AS has been shown in recent years, the relationship between disease that lipid peroxidation can promote the occurrence and development of the AS. Found in rabbit to produce chronic hyperlipidemia model, ginseng stems Ye Zao glucoside (GSL) besides can obviously decrease TC, TG, beta lipoprotein (beta LP) content, higher in HDLC play a role of regulating lipid, also can significantly reduce the heart and liver tissue in product of lipid peroxide malondialdehyde (MDA) content, and inhibition of lipid peroxidation, effectively prevent the happening of the AS development [21].
After that, the scholars in experimental hyperlipidemia rats model further found that 20 S original ginseng diol saponins (PPDS), ginseng saponins Rb group (GRBS) and ginseng fruit saponins injection (IGFS) can significantly decrease TC, TG, LDLC, thromboxane A2 (TXA2), lipid peroxide (LOP) content and whole blood viscosity, and can improve in HDLC, plasma prostaglandin I2 (PGI2) and serum and liver SOD activity, also can make the TC/in HDLC and LDLC/in HDLC ratio decrease, PGI2 / TXA2 ratio increased significantly, that ginseng may by adjusting the metabolism of blood lipid and improve the ratio of PGI2 / TXA2 and correct the free radicals metabolism disorder so as to play a role of resistance to hardening of the arteries (22-24).
6. The Organic ginseng has hypoxia ability:
Research has confirmed that ginseng and ginseng saponin can really improve the ability of hypoxia. From such as [25] hypoxia effect mechanism of total saponins in panax ginseng study found that the total saponins of ginseng can obviously prolong the survival time of mice under the condition of hypoxia. The results confirmed that respectively 12.5, 25.0, 50.0 mg/kg of ginseng total saponins give oxygen bottles of small and medium-sized mice to fill the stomach, can increase hemoglobin levels, increases in the brain, heart, liver and muscle L lactic acid dehydrogenase (LDH) activity, reduce the lack of oxygen in the muscle lactic acid accumulation caused by glycolysis, which have significant effect hypoxia. Tibet also has a better ability to resist oxygen ginseng fruit, can obviously prolong the mice survival time under the condition of normal pressure closed anoxia, for lack of or could improve the myocardial ischemia [26].
In any single active ingredients of ginseng and ginseng saponins of ginseng has certain cardiovascular pharmacological effects: can adjust the function of cardiovascular system, against a variety of animals, a variety of myocardial ischemia and myocardial injury caused by ischemia/reperfusion model. The present study more have ginseng saponins Rb1, and ginseng saponins of ginseng saponins Re Rg1, and less research of ginseng saponins other ingredients, deal with other ingredients for more research. Ginseng saponins parts widely, mechanism is complex, there are many aspects still need to be further discussed. Such as: ginseng total saponins on myocardial ischemia-reperfusion injury mechanisms of the protective effect of concentration and effect relationship;Booster function of PTS is due to the central vascular central motor excitation, contraction or direct effects on peripheral blood vessels;Ginseng saponins dilate blood vessels role is associated with endothelial cells, but what is action pathway and so on still need further research.
Misunderstandings about ginseng:
Misunderstandings 1: Eat ginseng were body get inflamed and heat.
Eat ginseng were Eat ginseng were body get inflamed and heat.Is this point of view is one-sided, not correct.is the maximum distortion and misunderstanding of ginseng, ginseng efficacy, especially the perennial wild ginseng, ginseng is not excessive taking it. otherwise counterproductive, symptoms such as hot and dry, nosebleeds, mouth sores, this is the consequence of human consumption caused by excess, is not the fault of ginseng, so, according to the dose, ginseng eat to quantificational everyday, as long as according to the standard dosage eat ginseng, everyday eat won't get inflamed,earthurn, more best nourishing effect,
Misunderstandings 2: Canot eat ginseng in the summer
Someone says "eat ginseng heat in summer, this statement is wrong, on a hot summer day, the body energy will consume too much, and ginseng can complement the energy dissipations of the body, improve body in summer vitality, sometimes taking participants feel the heat, but confirmed by experts, the summer can eat ginseng, but the number of taking ginseng cannot beyond the standard dosage.
Misunderstandings 3: young people don't eat ginseng
a lot of people think that youth people can not eat ginseng, this kind of view is incorrect, is old and one-sided, young and old to eat ginseng is different, the purpose of the young is make something perfect even more perfect, old people is a nice surprise and provide timely help, young people eat ginseng to report more energy, physical strength is more abundant, more dynamic, old people eat ginseng mainly cure is given priority to, nourishing is complementary, improve the body immunity.Enhance physical fitness, prolong life.
Misunderstandings 4: children cannot eat ginseng
"Children cannot eat ginseng" this view is wrong, medical certificate, the children eat ginseng is good, to eat, but must need to strictly control the number of ginseng.Children's long-term moderate taking ginseng, be beneficial to children's brains, flexible body development, intelligent and healthy growth, improve body immunity, enhance physical fitness.In the south, the spring and autumn winter, give the child take ginseng soup, has the moisture resistance, cold resistance effect is best.Two or three months in South Korea, the child is born, then feed the ginseng tonic, and has no side effects.
Organic ginseng:
Organic ginseng is in the process of organic cultivation environment, without the use of synthetic fertilizers and pesticides ginseng.Ginseng growth spray in inorganic fertilizers pesticides in soil, due to long-term erosion by chemical fertilizers, soil contains minerals is a severe lack of, so the growth of plants containing alkaline mineral deficiency, partial acid, if long-term consumption of this kind of inorganic acid food, can lead to many diseases, especially cancer of the incentives;Ginseng grown in organic is no spraying chemical fertilizers in soil, soil contains minerals is very rich, so the growth of ginseng contain alkaline minerals is very good, this kind of natural, pure, pollution-free organic food is healthy, alkaline food, long-term consumption can reduce disease, have anti-cancer, anti-cancer effect.Organic ginseng advocates maintain product natural ingredients, not polluted by fertilizers pesticides the day after tomorrow, so the ginseng taste thick.And ordinary ginseng due to long-term erosion by chemical fertilizers, not only taste is weak, more important is to destroy the original effectiveness and ginseng nutrients.Therefore, we advocate eating organic ginseng. ginseng is rare and precious ,medicine food homology-pure natural health tonic acura.Chinese emperors tributes.